Dr. Ray Clouse M.D. (1951-2007) Professor of Medicine and of Psychiatry
Washington University School of Medicine
Dr. Clouse’s contributions in motility, while many and significant, were but a fraction of his overall accomplishments in medicine and psychiatry
Contributions in motility
Developed the first motility disorder classification system based on underlying pathophysiological causes.
Established that certain classes of motility disorders often have neuropsychiatric sources and pioneered the use of anti-depressants for their treatment.
Established causal relationships between numerous systemic disease states and their manometric and endoscopic manifestations.
Contribution in high-resolution manometry
Produced first high-resolution topographical images of esophageal physiology
Produced first HRM characterization of esophageal landmarks and physiology
Led pioneering work in describing esophageal disorders using HRM
Contributions to ManoScan™ and SSI
Main contributor to successful NIH grants (highest scientific review scores) that funded ManoScan360™ and ManoScan HD™ developments.
Core collaborator in system design, clinical application, and diagnostic output.
Visionary in new diagnostic product concepts and directions.
Ray had the ability to gracefully merge the intellectual, the practical, and the aesthetic into extraordinary results. We are fortunate to have worked closely with him over the years and feel a deep void with his passing.